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How are monocytes larger than capillaries?


Why are new vessels more permeable in microvasculature?Manifestations of open foramen ovale in adultsIn an open circulatory system, how is blood moved?How do you determine if donated, stored blood is viable?Is pulse rate measurable in the capillary bed and venous vasculature?Do our blood vessels exude chemicals?Does capillary blood pressure have any effect on how much oxygen or nutrient gets distributed to tissues?Do blood vessels expand during angiogenesis?Are there macrophages in the blood vessels and within the blood stream?When endothelial cells in blood vessels (arteries or veins) are damaged, does atheroma form first or blood clot?













4












$begingroup$


I have read that the average size of a capillary is about 8 micrometers. How is it possible that the 15 micrometer or so monocytes in blood do not block these vessels?



https://en.m.wikipedia.org/wiki/Blood_vessel#Vessel_size



https://www.britannica.com/science/monocyte










share|improve this question









$endgroup$
















    4












    $begingroup$


    I have read that the average size of a capillary is about 8 micrometers. How is it possible that the 15 micrometer or so monocytes in blood do not block these vessels?



    https://en.m.wikipedia.org/wiki/Blood_vessel#Vessel_size



    https://www.britannica.com/science/monocyte










    share|improve this question









    $endgroup$














      4












      4








      4





      $begingroup$


      I have read that the average size of a capillary is about 8 micrometers. How is it possible that the 15 micrometer or so monocytes in blood do not block these vessels?



      https://en.m.wikipedia.org/wiki/Blood_vessel#Vessel_size



      https://www.britannica.com/science/monocyte










      share|improve this question









      $endgroup$




      I have read that the average size of a capillary is about 8 micrometers. How is it possible that the 15 micrometer or so monocytes in blood do not block these vessels?



      https://en.m.wikipedia.org/wiki/Blood_vessel#Vessel_size



      https://www.britannica.com/science/monocyte







      immunology hematology cardiology blood-circulation circulatory-system






      share|improve this question













      share|improve this question











      share|improve this question




      share|improve this question










      asked Jun 23 at 2:20









      Hypnos StratagemHypnos Stratagem

      534 bronze badges




      534 bronze badges




















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          $begingroup$

          They aren't completely rigid and can change shape to squeeze through (see Downey et al).



          If they are activated, monocytes can get stuck in capillaries and block them, which contributes to poor circulation following reperfusion after an ischemic blockage (see Engler et al).




          Downey, G. P., Doherty, D. E., Schwab 3rd, B., Elson, E. L., Henson, P. M., & Worthen, G. S. (1990). Retention of leukocytes in capillaries: role of cell size and deformability. Journal of applied physiology, 69(5), 1767-1778.



          Engler, R. L., Schmid-Schönbein, G. W., & Pavelec, R. S. (1983). Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog. The American journal of pathology, 111(1), 98.






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            6












            $begingroup$

            They aren't completely rigid and can change shape to squeeze through (see Downey et al).



            If they are activated, monocytes can get stuck in capillaries and block them, which contributes to poor circulation following reperfusion after an ischemic blockage (see Engler et al).




            Downey, G. P., Doherty, D. E., Schwab 3rd, B., Elson, E. L., Henson, P. M., & Worthen, G. S. (1990). Retention of leukocytes in capillaries: role of cell size and deformability. Journal of applied physiology, 69(5), 1767-1778.



            Engler, R. L., Schmid-Schönbein, G. W., & Pavelec, R. S. (1983). Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog. The American journal of pathology, 111(1), 98.






            share|improve this answer









            $endgroup$

















              6












              $begingroup$

              They aren't completely rigid and can change shape to squeeze through (see Downey et al).



              If they are activated, monocytes can get stuck in capillaries and block them, which contributes to poor circulation following reperfusion after an ischemic blockage (see Engler et al).




              Downey, G. P., Doherty, D. E., Schwab 3rd, B., Elson, E. L., Henson, P. M., & Worthen, G. S. (1990). Retention of leukocytes in capillaries: role of cell size and deformability. Journal of applied physiology, 69(5), 1767-1778.



              Engler, R. L., Schmid-Schönbein, G. W., & Pavelec, R. S. (1983). Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog. The American journal of pathology, 111(1), 98.






              share|improve this answer









              $endgroup$















                6












                6








                6





                $begingroup$

                They aren't completely rigid and can change shape to squeeze through (see Downey et al).



                If they are activated, monocytes can get stuck in capillaries and block them, which contributes to poor circulation following reperfusion after an ischemic blockage (see Engler et al).




                Downey, G. P., Doherty, D. E., Schwab 3rd, B., Elson, E. L., Henson, P. M., & Worthen, G. S. (1990). Retention of leukocytes in capillaries: role of cell size and deformability. Journal of applied physiology, 69(5), 1767-1778.



                Engler, R. L., Schmid-Schönbein, G. W., & Pavelec, R. S. (1983). Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog. The American journal of pathology, 111(1), 98.






                share|improve this answer









                $endgroup$



                They aren't completely rigid and can change shape to squeeze through (see Downey et al).



                If they are activated, monocytes can get stuck in capillaries and block them, which contributes to poor circulation following reperfusion after an ischemic blockage (see Engler et al).




                Downey, G. P., Doherty, D. E., Schwab 3rd, B., Elson, E. L., Henson, P. M., & Worthen, G. S. (1990). Retention of leukocytes in capillaries: role of cell size and deformability. Journal of applied physiology, 69(5), 1767-1778.



                Engler, R. L., Schmid-Schönbein, G. W., & Pavelec, R. S. (1983). Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog. The American journal of pathology, 111(1), 98.







                share|improve this answer












                share|improve this answer



                share|improve this answer










                answered Jun 23 at 2:38









                Bryan KrauseBryan Krause

                20.3k3 gold badges34 silver badges60 bronze badges




                20.3k3 gold badges34 silver badges60 bronze badges



























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